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Between 2020 and 2025, Guadalupe County saw a 15.76% population increase, according to county-level data released by the U.S. Census Bureau in March.
In 2020, Guadalupe County had an estimated population of 173,722, which increased to an estimated population of 201,111 in 2025, data shows.
The overview: The largest contributor to population growth in Guadalupe County is domestic migration, according to data from the bureau. Domestic migration refers to individuals moving across county or state lines. International migration refers to individuals who cross a national border between two countries, according to the bureau.
In both annual and cumulative measurements, the natural population growth in the county increased, meaning more county residents were born than died. Between 2024 and 2025, the census data found that there were 2,058 births and 1,433 deaths in the county.
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